Gum Disease & Alzheimer's: The P. gingivalis Link | Dr. Ed Zuckerberg
March 23, 2023
Can a bacteria in your patients' gums affect the brain, the heart and blood sugar? Dr. Ed Zuckerberg, chief dental officer for Keystone Bio, explains how toxins from P. gingivalis may travel far beyond the mouth, a monoclonal antibody being developed against it, and saliva tests that screen for oral and throat cancer. In this episode: - From a Brooklyn practice to a dental office in his home - The 3 a.m. emergency that brought 50 referrals - How Howard Farran and Facebook started his lecturing career - Advising dental startups and Revere Partners - P. gingivalis and its links to Alzheimer's, diabetes and heart disease - His own P. gingivalis test results - A monoclonal antibody that kept P. gingivalis away for months in an early study - Saliva testing for oral cancer and the oral microbiome - Why dentists should be part of primary care Plus dental news: dentists' opioid prescribing is down, dental ER visits rose during the shutdown, new CDT sleep apnea codes for 2024, and employee retention credit scams. Dr. Ed Zuckerberg graduated from NYU College of Dentistry in 1978 and practiced in Brooklyn and Dobbs Ferry, New York, until 2013. An early adopter of digital radiography, CAD/CAM and the paperless office, he lectures on technology in the dental office, advises dental startups, and is chief dental officer for Keystone Bio. He is the father of Facebook founder Mark Zuckerberg. Chapters: 0:00 Intro 1:27 Welcome Shofu, our new educational partner 2:07 News: the dentist accused of poisoning his wife 2:44 News: dentists' opioid prescribing is down 5:43 News: dental ER visits rose during the shutdown 8:49 News: CDT comment period and new sleep apnea codes 9:38 News: employee retention credit scams 10:39 Introducing Dr. Ed Zuckerberg 13:14 Practicing in Brooklyn, then in his home 15:23 The 3 a.m. emergency that brought 50 referrals 18:49 Howard Farran, Facebook and Dentaltown 20:51 Lecturing on technology, and the move to California 22:51 Advising dental startups 24:36 Revere Partners and Keystone Bio 25:50 P. gingivalis: one bug, many diseases 27:37 The patients he couldn't convince 29:24 How P. gingivalis toxins reach the brain, liver and heart 32:40 His own P. gingivalis test 34:07 A monoclonal antibody against P. gingivalis 36:26 How it would be used in the dental office 38:42 A saliva test for oral and throat cancer 41:57 Who should be screened 43:59 Reviewing results like blood work 45:26 Billing for saliva testing 46:45 Diet advice from the oral microbiome 49:20 Dentists as primary care 52:37 Giving patients answers 54:20 Independent dentists vs corporate dentistry 56:16 Closing and Ed's wildlife photography 🎧 Listen to the podcast: Apple Podcasts: https://podcasts.apple.com/us/podcast/dentists-in-the-know/id1543254763 Spotify: https://open.spotify.com/show/2Elfj6LX0hCUyp0AgdTsij 📺 Make sure you subscribe to catch new episodes live every Wednesday at 8pm ET! https://www.youtube.com/@dentistsintheknow 🌟 Stay up to date on all the latest dental trends when you follow the DINKs: https://fanflet.com/dinks/social-2